Dermatomyositis is a frequent infected illness recognized by muscle tissue listlessness and typical pores and skin fast. Dermatomyositis impacts kids and parents alike.
In parents, dermatomyositis usually appear from their late 40s to early 60s, in kids, the illness occurs most often between the ages of 5 to 15 years. Dermatomyositis menyeran more women than men.
One type of dermatomyositis is polymyositis, infected muscle tissue illness that causes muscle tissue listlessness that control movement.
Symptom
The most frequent symptoms of dermatomyositis, among others;
1. Stained pores and skin. The fast is red or purplish-black, most often found on the face, eye lids, area around the nails, knuckles, hand, legs, chest, and back. The fast is distributed with bluish pink lines is the first sign of dermatomyositis.
2. Muscle listlessness. Modern muscle tissue listlessness menterang muscle mass close to the center of your shape such as body, thighs, shoulders, upper arms and neck. This listlessness impacts the left and right area of your shape, and tends to decline slowly.
The symptoms of Dermatomyositis that may occur:
1. Difficulty taking (dysphagia)
2. Muscle pain
3. Exhaustion, nausea and weight loss
4. Solidifying of calcium supplement remains under the pores and skin (calcinosis), especially in children
5. USU gastritis and sores are also more frequent in children
6. Trouble in the lung
Cause
The exact cause of dermatomyositis is unknown, but this illness has many commonalities with reduced natureal defenses that invasion normal shape components.
Normally, the defense mechanisms deliver the results to protect balanced tissue from invasion by foreign materials, such as bacteria and infections. Without a known cause, the defense mechanisms begins producing autoimmune antibodies (autoantibodies) that invasion the body's own tissues.
Small veins in muscle mass is the most quickly affected by dermatomyositis. Inflamed tissue that encompass veins and eventually causing damage to muscle tissue materials.
Treatments and drugs
There is no cure for dermatomyositis, but procedure method can be given to develop the perform of the pores and skin and muscle tissue energy. There is no single best technique, the medical professional will custom procedure method strategies based on the indications and symptoms and how well the illness is addressing remedy.
Corticosteroids
For most individuals, the first step in the procedure method of dermatomyositis is a corticosteroid drugs use. To mnegatasi dermatomyositis, usually the drugs of choice is prednisone.
Corticosteroids are medications that control the defense mechanisms, decreasing the production of antibodies, reducing irritation of muscle tissue and improve energy and muscle tissue perform. The medical professional may also advocate relevant adrenal cortical steroids to the pores and skin.
Your medical professional may start by suggesting high amounts of adrenal cortical steroids and then reduce if the indications improved. Recovery generally takes about two to four months, but individuals can still take drugs for several months. Long-term use of adrenal cortical steroids can have serious negative results, which is why physicians are slowly cheaper the serving of drugs to a cheaper level. Your medical professional may advocate calcium supplement and vitamin D supplements to reduce these negative results.
Additional immunosuppressive therapy
If corticosteroid drugs will not deliver the results efficiently, your medical professional may suggest to add or switch to another drugs, namely;
1. Corticosteroid-sparing. When combined with adrenal cortical steroids, corticosteroid-sparing drugs may reduce the serving and negative results of adrenal cortical steroids. These drugs contain azathioprine (Azasan, Imuran) or methotrexate (Trexall, Methotrexate, Rheumatrex).
Your medical professional may advocate azathioprine or methotrexate together with prednisone if the illness is progressive or the individual has a additional complications issue. Some physicians advocate these drugs as first strategy to individuals who are not advised to use adrenal cortical steroids.
2. Medication immunoglobulin (IVIG). IVIG is a pure shape that contains antibodies from thousands of balanced shape contributors. Healthy antibodies in IVIG can block the antibodies that invasion the muscle mass and pores and skin in dermatomyositis.
The procedure method is used by infusion through a vein. IVIG benefits but does not last extensive. Infusion should be frequent every six to eight months.
3. Other immunosuppressive drugs. Tacrolimus (Prograf) is a drugs that may deliver the results to prevent the defense mechanisms. Topical tacrolimus is often used to cure dermatomyositis and other pores and skin difficulties. Oralnya serving forms are useful to cure dermatomyositis complicated by interstitial lung illness.
Biological therapy
If the case is severe and other treatments fail, your medical professional may advocate one of the third line strategy to treating dermatomyositis:
1. Rituximab (Rituxan) has been researched in a few individuals with polymyositis and dermatomyositis can develop muscle tissue energy, conquer the additional complications of the lung area, and pores and skin fast.
2. Growth necrosis issue (TNF) inhibitors such as etanercept (Enbrel) and infliximab (Remicade) is a drugs that focuses on key protein that cause irritation.
There has been no research exist to date about the effectiveness of drugs for dermatomyositis. If physicians advocate one drugs, it will monitor individuals to ensure the medicine deliver the results and examine the negative results.
Another approach
Other treatments that can direkomensdasikan medical professional include:
1. Antimalarial drugs. For the fast, the medical professional may advocate anti-malarial drugs such as hydroxychloroquine (Plaquenil) or chloroquine (Aralen).
2. Anaesthetic. Drugs such as discomfort, motrin (Advil, Motrin, others) and acetaminophen (Tylenol, others) can be used to cure suffering. If this is not adequate, your medical professional may advocate healthier suffering medications such as codeine.
3. Treatment method. A physiotherapist can demonstrate exercises to maintain and improve muscle tissue energy and flexibility and advise an appropriate activity.
4. Conversation remedy. If the individual has difficulties taking, speech remedy can help him learn how to cover for such changes.
5. Dietetic assessment. When eating and taking food becomes more difficult. Nutritionist can teach you how to prepare foods that are quickly eaten.
6. Surgery. Procedures can be an option to remove painful calcium supplement accumulate and prevent frequent pores and skin illness.
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